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KMID : 0391019980060010016
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Journal of Korean Society for Clinical Pharmacology and Therapeutics
1998 Volume.6 No. 1 p.16 ~ p.24
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Nonparametric PK/PD Analysis of Controlled-Release Formulations Showing Double Peak Concentrations : Application of the Spline Function
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유경상/Kyung Sang Yu
배균섭/장인진/신상구/조수헌/신완균/Kyun Seop Bae/In Jin Jang/Sang Goo Shin/Soo Hun Cho/Wan Gyoon Shin
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Abstract
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KEYWORD
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Diltiazem, Controlled-release, Spline, Mixed-effect modeling, Pharmacokinetics,
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